Cookie Notice

We use cookies to make parts of our website work, and to improve your visitor experience.
If you only allow necessary cookies, some features of our website may not work.

Engineering news

Bacteria-killing insect wings reveal secrets for antimicrobial implants

Professional Engineering

An E. coli bacterium on a bed of 'nano nails' (Credit: Professor Bo Su, University of Bristol)
An E. coli bacterium on a bed of 'nano nails' (Credit: Professor Bo Su, University of Bristol)

Researchers have revealed hidden details of how insect wings kill bacteria, showing a potential route for antimicrobial human implants.

While some insects such as cicadas and dragonflies are known to kill bacteria that touch ‘nanopillar structures’ on their wings, the precise mechanisms were previously unknown. A team at the University of Bristol used a range of advanced imaging tools and experimental techniques to identify ways in which nanopillars can damage bacteria.

The researchers, led by professor of biomedical materials Bo Su, said the “important” findings will aid the design of better antimicrobial surfaces for potential biomedical applications such as medical implants and devices that are not reliant on antibiotics.

“Now we understand the mechanisms by which nanopillars damage bacteria, the next step is to apply this knowledge to the rational design and fabrication of nanopatterned surfaces with enhanced antimicrobial properties,” said Su.

“Additionally, we will investigate the human stem cell response to these nanopillars, so as to develop truly cell-instructive implants that not only prevent bacterial infection but also facilitate tissue integration.”

Scientists previously believed that nanopillars kill bacteria by puncturing the cells, causing them to disintegrate. However the new study showed that antibacterial effects of nanopillars come from a range of factors, and are dependent on species and the ‘nanotopography’ of wings.

“Alongside deformation and subsequent penetration of the bacterial cell envelope by nanopillars, particularly for Gram-negative bacteria, we found the key to the antibacterial properties of these nanopillars might also be the cumulative effects of physical impedance and induction of oxidative stress,” said Su.

“We can now hopefully translate this expanded understanding of nanopillar-bacteria interactions into the design of improved biomaterials for use in real world applications.”

The research, which was funded by the Medical Research Council, was published in Nature Communications.

Want the best engineering stories delivered straight to your inbox? The Professional Engineering newsletter gives you vital updates on the most cutting-edge engineering and exciting new job opportunities. To sign up, click here.

Content published by Professional Engineering does not necessarily represent the views of the Institution of Mechanical Engineers. 


Read more related articles

Professional Engineering magazine

Current Issue: Issue 3, 2023

Issue 3 cover 2023 online
  • The AI explosion
  • Making engineering fun 
  • Skills re-energised 

Read now

Professional Engineering app

  • Industry features and content
  • Engineering and Institution news
  • News and features exclusive to app users

Download our Professional Engineering app

Professional Engineering newsletter

A weekly round-up of the most popular and topical stories featured on our website, so you won't miss anything

Subscribe to Professional Engineering newsletter

Opt into your industry sector newsletter

Related articles